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The present study assessed the potential hepatoprotective effects of phytic acid (PA), a natural antioxidant and iron chelator, on APAP-induced hepatotoxicity and the possible underlying mechanism through its effects on CYP2E1 gene expression, iron homeostasis, oxidative stress, and SIRT -1 expression levels

These ROS can trigger and amplify inflammatory responses, creating a cycle of tissue damage and immune dysfunction

Conversely, maintaining optimal glutathione levels supports robust immune cell function and may enhance the body's natural defense mechanisms

Some peptides have been studied for their ability to support gastrointestinal tissue health and gut barrier integrity

Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test

Vitamin D overdose may cause hypercalcemia, vomiting, polydipsia, dehydration, constipation, pain, loss of appetite, and cardiovascular and renal complications [156,157]